Dr Suzanne Estaphan

PhD, MBBCh, MSc
Lecturer in Medical Science, ANU Medical School, Acton campus

Suzanne Estaphan is a motivated, energetic and outgoing medical teacher and researcher. She was granted her M.B.B.Ch. in 2005, Diploma of Pediatrics in 2009, MSc of Physiology in 2012, Doctorate of Physiology in 2015, and Basic certificate in Medical Education in 2018.

Suzanne has held multiple clinical and academic positions across her career. Currently she is a Lecturer in medical Sciences (Physiology), ANU School of Medicine and Psychology, where she convenes a number or undergraduate and postgraduate courses across the Bachelor of Health Science (BHLTH) and the medical programs (MCHD), and actively contributes to ANU Medical School Admissions, assessment committee, and Curriculum committees. Dr. Estaphan started her academic work in teaching medical Physiology and mentoring medical students since 2008, and started her clinical career since 2006 where she graded up from house officer, pediatrics resident up to pediatrics specialist since 2010.

Dr Estaphan is a recognised reviewer for high ranked journals including Antioxidants and Redox Signalling journal and the Journal of Physiology and Biochemistry. In 2023 she was invited to join the editorial board of Frontiers in Physiology journal as a review editor. She has presented her work at various high profile international conferences and was awarded 'The American Physiological Society Travel Award in 2017.

Specialisation

  • Medical Science

Research interests

Dr Estaphan studies the role of oxidative stress and inflammation in the physiology and the pathophysiology of different medical conditions and explores potential interventions including antioxidant drugs.

To date, she has over a dozen publications in this area and has attracted approximately $200,000 in funding. Her research has looked at the effect of oxidative damage to the kidney, liver, brain, pancreas and bones.

Her newest projects aim to explore the sleep dysfunction in people with eating disorders, and whether a drug used to control blood glucose levels in people with type 2 diabetes can impact a person's ability to exercise.

In addition to her oxidative stress and disease cycle work, Suzanne has an interest in medical education research. At the height of the pandemic, as part of the ANU response to COVID-19, Suzanne completed research about social studying and on student's use of learning resources.

Dr Estaphan continues to be actively involved in medical education research currently co-leading a project about clinical reasoning in learning, and is contributing to a national project that aims to Achieve Consensus on the Core Concepts of Physiology.

  • Naguib, M, Abdel-Razek, W, Estaphan, S et al. 2022, 'Impact of prothrombin and factor V Leiden mutations on the progression of fibrosis in patients with chronic hepatitis C', PLOS ONE (Public Library of Science), vol. 17, no. 11.
  • Sabry, M, Mostafa, S, Rashed, L et al. 2021, 'Matrix metalloproteinase 9 a potential major player connecting atherosclerosis and osteoporosis in high fat diet fed rats', PLOS ONE (Public Library of Science), vol. February 11, 2021, pp. 1-16.
  • Sabry, M, Mostafa, S, Kamar, S et al. 2021, 'The cross-talk between Matrix metalloproteinase-9, RANKL/OPG system and cardiovascular risk factors in ovariectomized rat model of postmenopausal osteoporosis', PLOS ONE (Public Library of Science), vol. 16, no. 10.
  • Estaphan, S, Curpan, A, Khalifa, D et al. 2021, 'Combined low dose of ketamine and social isolation: A possible model of induced chronic schizophrenia-like symptoms in male albino rats', Brain Sciences, vol. 11, no. 7.
  • Hassona, M, Radwan, E, Abdelsameea, E et al. 2021, 'The Putative Role of Natural Killer Cells in Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma', Asia Pacific Journal of Cancer Prevention, vol. 22, no. 8, pp. 2559-2567.
  • Estaphan, S, Abdel-Malek, R, Rashed, L et al. 2020, 'Cimetidine a promising radio-protective agent through modulating Bax/Bcl2 ratio: An in vivo study in male rats', Journal of Cellular Physiology, vol. 235, no. 11, pp. 8495-8506.
  • Younan, N, Elattar, S, Farouk, M et al. 2019, 'Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats', Physiological Reports, vol. 7, no. 17, pp. 1-13.
  • Dawood, A, Sabry, M, Estaphan, S et al. 2018, 'Cross-talk between apelin and vasopressin in response to different osmotic stimuli in type 2 diabetic rats', Journal of Biological Regulators and Homeostatic Agents, vol. 32, no. 5, pp. 1117-1127.
  • Elattar, S, Estaphan, S, Mohamed, E et al. 2017, 'The protective effect of 1alpha, 25-dihydroxyvitamin d3 and metformin on liver in type 2 diabetic rats', Journal of Steroid Biochemistry and Molecular Biology, vol. 173, no. 15, pp. 235-244.
  • Estaphan, S, Eissa, H, Elattar, S et al. 2015, 'A study on the effect of cimetidine and l-carnitine on myoglobinuric acute kidney injury in male rats', Injury: international journal of the care of the injured, vol. 46, no. 7, pp. 1223-12130.
  • Eissa, H, Mohamed, N, Mousa, M et al. 2011, 'A study on the effect of sildenafil citrate on acute renal ischemic-reperfusion injury in male rats', Medical Journal of Cairo University.